By up‐regulating the expression levels of peroxisome proliferators activated receptor alpha (PPARα) and sterol regulatory element binding protein‐1 (SREBP‐1), two important gene regulators involved in hepatic lipid metabolism could recuperate diabetic and oleic acid‐induced NAFLD or NASH, in turn affecting liver cancer.52 The gene discussed is SREBF1; the disease is metabolic dysfunction-associated steatotic liver disease.