In addition, CGA indirectly influences the development of liver cancer by inhibiting the activation of NF‐κB and JNK/AP1 and blocking the signalling pathway of transforming growth factor‐β1 (TGF‐β1)/SMAD Family Member 7 (SMAD7) regulated by miR‐21.139, 140. This evidence concerns the gene SMAD7 and liver cancer.