In human neuroblastoma cell line SHSY5Y, overexpression of WT KIF26A, but not variant KIF26As, stabilizes microtubules, making them resistant to depolymerization induced by Nocodazole treatment, a small molecule commonly used for this purpose (Figure 1F and Figure S2B) (Vasquez et al., 1997). The gene discussed is KIF26A; the disease is neuroblastoma.