Through qRT-PCR, we observed that BAG3 mRNA expression in BC tissues was increased compared with that in the control group (Fig. 3G), and BAG3 mRNA expression was increased in 95.9% cases (47 of 49 cases) (Fig. 4H), and BAG3 mRNA was negatively correlated with miR-135a-5p expression in BC samples (Fig. 3I). Here, BAG3 is linked to breast cancer.