At 56-days post-infection, 11 mouse serum proteins were up-regulated (various Ig kappa and heavy chains, haptoglobin, inter-alpha-trypsin inhibitor heavy chain H3, complement factor [H and B], ceruloplasmin, and F-box/LRR-repeat protein 12) and 19 were down-regulated (various keratin types, MAGUK p55 subfamily member 4, serum amyloid A-4 protein, serine protease inhibitors, macrophage erythroblast attacher, actin alpha cardiac muscle 1, apolipoprotein M, and hemoglobin subunit epsilon-Y2). This evidence concerns the gene HP and infection.