At 56-days post-infection, two proteins, inter-alpha-trypsin inhibitor heavy chain H3 and ceruloplasmin, were up-regulated: while inter-alpha-trypsin inhibitor heavy chain H3 is related to inflammation and carcinogenesis [54, 55], ceruloplasmin is a serum glycoprotein related to the acute phase of infection. The gene discussed is ITIH3; the disease is infection.