Similarly, analysis of human sarcoma and carcinoma cell lines identified areas of synergistic interaction with Gem + DAC treatment, particularly in the embryonal rhabdomyosarcoma line RD, the alveolar rhabdomyosarcoma cell line SJRH30, and the pancreatic ductal adenocarcinoma cell line MIA PaCa-2 (Supplemental Figures 3, 4, 6, and 7). This evidence concerns the gene GEM and carcinoma.