Denkert Denkert C C Huober Huober J J Loibl Loibl S S HER2 and ESR1 mRNA expression levels and response to neoadjuvant trastuzumab plus chemotherapy in patients with primary breast cancer HER2 and ESR1 mRNA expression levels and response to neoadjuvant trastuzumab plus chemotherapy in patients with primary breast cancer Breast Cancer Res Breast Cancer Res 2013 2013 15 15 R11 R11 10.1186/bcr3384 10.1186/bcr3384 supplied-pmid 23391338? The gene discussed is ESR1; the disease is breast cancer.