Several cytokines that activate JAK/STAT signaling, including interferon-γ, granulocyte-macrophage colony-stimulating factor, IL-2, and IL-6, are overexpressed in patients with COVID-19 (13, 14), and inhibiting some of these inflammatory mediators is associated with clinical improvement compared with standard of care (10, 15, 16). The gene discussed is IL6; the disease is COVID-19.