It is considered the most studied mutation in HIV-1 immunogenetics because it has been associated with relative disease resistance since 1996.85 The outcome of the presence of this mutation in the phenotypic manifestation of the disease is the control of the inflammatory response since this control is related to the progression of autoimmune and infectious diseases.89 CCR5 Δ32 to date is the only genetic mutation that completely blocks HIV-1 infection in humans.70 The gene discussed is CCR5; the disease is infectious disease.