Additionally, we were unable to obtain some effective indicators for predicting RCC-BM from SEER, such as transforming growth factor-β (TGF-β) [35], fibroblast growth factor (FGF) [1], insulin-like growth factor [36], bone morphogenetic protein [37], AFP [38], CA-199 [31], and Fuhrman nuclear grade [39]. The gene discussed is AFP; the disease is renal cell carcinoma.