Analysis of proteomic data also revealed differential expression of FDX1 in the tumors, among which FDX1 expression level was lower in colon adenocarcinoma (COAD), glioblastoma multiforme (GBM), head and neck squamous cell carcinoma (HNSC), lung adenocarcinoma (LUAD) and pancreatic adenocarcinoma (PAAD) compared with normal tissues; while higher in breast invasive carcinoma (BRCA), ovarian serous (OV) and uterine corpus endometrial carcinoma (UCEC) (Figure 1C). The gene discussed is FDX1; the disease is lung adenocarcinoma.