TRIP13 and malignant colon neoplasm: Zhu et al. (2019) found that TRIP13 was the most prominent differentially expressed AAA ATPase gene and a promising candidate oncogene in liver cancer. In addition, the TRIP13 mRNA level was upregulated in peripheral blood in colon cancer tissues, thus making it a potential target for early-stage diagnosis (Soylemez et al., 2021).