Although the repressing activity of P53 on SLC7A11 expression has been reported in U2OS and MCF7 human cell lines (Jiang et al., 2015), in HCT116TP53−/− colon cancer cells P53 stimulates, instead of repressing, SLC7A11 expression. The gene discussed is SLC7A11; the disease is malignant colon neoplasm.