TP53 and non-small cell lung carcinoma: Table 1 shows the clinical information of 950 patients in the TCGA database. The age at diagnosis was 90 years at the maximum and 33 years at the minimum, with a median age of 67 years. There were approximately 758 (79.79%) stage I-II patients and 192 (20.21%) stage III-IV patients. TP53 gene mutation occurred in 642 (67.58%) NSCLC patients. The baseline clinical data that includes age, gender, TNM stage, and TP53 mutation status of two NSCLC patients sets were comparable (p > 0.05, Table 1).