The result of KEGG-GSEA indicated that the PCGs of GS-like group were enriched in pathways associated with tumor microenvironment including PPAR signaling pathway, cytokine-cytokine receptor interaction, and cell adhesion molecules (CAMs), meanwhile PCGs of GU-like group were enriched in pathways associated with genomic instability consisting of cell cycle, homologous recombination, nucleotide excision repair and mismatch repair (Figures 4C,D). This evidence concerns the gene PPARA and neoplasm.