Moreover, some studies have shown that METTL1 was associated with the immunosuppressive tumor microenvironment and stemness indices, and that its expression reflected the sensitivity of immune checkpoint blockade (ICB) therapy (Ma et al., 2021; Tian et al., 2019; Dai et al., 2021; Liu et al., 2019; Gao et al., 2022). Here, METTL1 is linked to neoplasm.