By analyzing 450K Illumina methylation array data from TCGA, we detected a PCa-associated differentially methylated region (DMR) within the predicted IRAK1-promoter (hg19 chrX:153283694-153284103) (TU, N=341; NOR, N=35; HMM-Fischer test, p<1.8x10-10, Figure 3A). The gene discussed is IRAK1; the disease is posterior cortical atrophy.