The expression of genes encoding the main components of the Myddosome complex, IRAK1, IRAK4 and MYD88, and the adaptor protein TRAF6 were assigned to specific cell types within PCa using scRNA-seq data generated from eight radical prostatectomy (RP) specimens from men with localized PCa (17) (Figure 1 and Table S1). The gene discussed is IRAK4; the disease is posterior cortical atrophy.