TNF and metastatic malignant neoplasm in the lymph nodes: According to the analysis of risk factor, we can also draw the conclusion that lymph node metastasis and TNM staging are statistically relevant to IL-6 and IL-12P7; in addition, the statistical correlation of degree of differentiation with TNF-α further suggests IL-6, TNF-α and IL-12P7 are closely related to the condition of patients.