Considering the importance of monocytes in acquired immunity after vaccination (10) including BNT162b2 vaccination (5), a thorough understanding of monocytes in BNT162b2-induced myocarditis (BNT162b2-MyoC) cases would give a new viewpoint regarding the pathogenesis of the event and provide biomarkers to rule out people at high risk in advance from vaccination. The gene discussed is MYOC; the disease is myocarditis.