Next, we evaluated the relevance of using IFN-γ response as a biomarker of hospitalization in COVID-19 patients using a receiver-operating characteristic (ROC) curve: the area under the ROC curve (AUC) was 87.9%, revealing a good performance of IFN-γ response in predicting hospitalization in COVID-19 patients. The gene discussed is IFNG; the disease is COVID-19.