We screened all metabolites due to C-phycocyanin intake (PC vs. CIS, p < 0.01; CIS vs. NC, p < 0.01; PC vs. NC, p > 0.05), and analyzed the correlation between these metabolites and the contents of Lactobacillus and NRF2 levels (Figure 7C). This evidence concerns the gene NFE2L2 and in situ carcinoma.