MYD88 and Alzheimer disease: It is worth noting that we found an increase in MyD88 expression in the cortical white matter of both the WE and AD patients when compared with the control case (p < 0.0001 and p = 0.0018, respectively), and such an increase was particularly prominent in the WE case (p < 0.0001, compared with the AD case) (Figures 3D–F; F (2, 21) = 139.4, p < 0.0001).