Significant disorder pathways (−log (P value) were larger, but no consistent activation or inhibition information were acute phase response signaling, completion system, glycolysis I, LXR/RXR activation, regulation of eIF4 and p70S6K Signaling, FXR/RXR Activation, gluconeogenesis I, adenine and adenosine salvage I, systemic lupus erythematosus signaling and mTOR signaling, etc. EIF2 signaling was the only pathway that was more significantly activated in D group (late exudate) than in B group (early exudate). Here, RPS6KB1 is linked to systemic lupus erythematosus.