Therefore, lncRNA ASncmtRNA-2, lncRNA NEAT1, lncRNA TUG1 and lncRNA Blnc1 reduce the damage associated with diabetes and its complications by regulating the ferroptotic factor ROS, while lncRNA MIAT and lncRNA MALAT1 inhibit ferroptosis by regulating the key regulatory factor Nrf2, thus slowing the development of diabetes and its complications (Figure 2). Here, PAQR9 is linked to diabetes mellitus.