IGHE and asthma: Prospective studies with randomization and standardized collection of pulmonary function tests, maxillofacial CT scans, serum IgE and complete blood counts with differential, and collection of SNOT-22, ACQ-5, ACT, and NOSE scores at regular intervals would provide useful increased data on the effect of biologic treatment in patients with asthma, allergic rhinitis, and chronic rhinosinusitis with sinonasal polyposis.