SMURF1 and Familial prostate cancer: For instance, FUS, modulated by circRNA_0000285, has been found to facilitate the development of cervical cancer [50]; FUS combines with circ0005276 to propel cell proliferation and migration of prostate cancer via the activation of XIAP transcription [51]; FUS participates in the development of thyroid cancer through the stabilization of SMURF1 [25]; and LINC00205 recruits FUS to facilitate the progression of lung malignancy [52].