To further understand the relationship between the expressed level of VAV1, RHOA, and ZC3HAV1, and the infiltration of immune cell types, the CIBERSORT algorithm was performed to evaluate the distributed difference of 22 immune cell subtypes in HCC patients within low- and high-risk group stratified by VAV1, RHOA, and ZC3HAV1, respectively. Here, RHOA is linked to hepatocellular carcinoma.