Although currently the mouse model that lacks all murine MHC molecules is only available for HLA-A*0201 and HLA-DRB1*0101, it will be interesting to compare the immune responses from AAD mice and A2.DR1 mice in the future and especially for the establishment of spontaneous HPV18 E6/E7-expressing cervical cancer model. Here, HLA-C is linked to cervical cancer.