The low MECs (25 μg/mL) that caused a reduction in the MICFCZ values of at least fourfold with the clinical isolates of Candida, highlighted A. communis and S. atriplicifolium as promising sources of Mdr1 and Cdr1 inhibitors to augment FCZ activity in the treatment for azole resistant candidiasis. This evidence concerns the gene CDR1 and candidiasis.