We found that a tumor sample classified as hormone-receptor positive (ER + PR +) has 1194 DNA regions identified as SEs associated to 1128 genes, while the remaining three TN tumors contained 640, 527 and 651 SEs associated to 610, 458, and 587 genes, respectively (Fig. 1A and Additional file. 1). Here, ESR1 is linked to neoplasm.