Figure 1 also shows that TIM3 (HAVCR2) and OX40 (TNFRSF4) are at the most left positions; they are differently expressed in 15 and 14 cancers types respectively, out of 31, followed by GITR (TNFRSF18), LAG3 and TIGIT, differently expressed in 12 and 10 and 9 cancers, respectively. Here, TIGIT is linked to cancer.