Seven biomarkers with abnormal levels were significantly associated with COVID-19 mortality, among which NT proBNP > 400 pg/mL was associated with a 2.4-fold higher odds of death, procalcitonin > 100 ng/L, lymphocyte counts < 1 × 103/uL, and ferritin > 300 ng/mL were associated with over 50% higher odds of death (Fig. 2). This evidence concerns the gene NPPB and COVID-19.