As expected, RT-qPCR results confirmed that the mRNA levels of tumor-related genes, WNT5A, ZMYND8, BCL2L1, CAV1, TBX2, STEAP3, POU2F2, EPHA2, KCNJ15, EPSTI1, PALMD, and S100A16 were significantly downregulated after GNE987 treatment in U87 cells. The gene discussed is POU2F2; the disease is neoplasm.