As macrophages grow in size when they phagocytose, we determined the phagocytic index, i.e., the number of macrophages that had engulfed γH2-AX-positive tumor cells (Figure 1D), reasoning that γH2-AX-positive nuclei in macrophages would be derived from tumor cells with BRCA1 loss given that the host macrophages are BRCA1 proficient. This evidence concerns the gene BRCA1 and neoplasm.