We lowered the tumor’s defense against macrophage-induced cell death and phagocytosis by blocking the “don’t-eat-me” signal, i.e., the immunoglobulin CD47 (Huang et al., 2017; Willingham et al., 2012), which was strongly expressed on tumor cells derived from K14-Cre BRCA1f/fp53f/f tumors (Figure S6E). Here, CD47 is linked to neoplasm.