One prior study showed potential for MEP1A with lower membranous staining in MOC compared with pancreatic cancers (46); however, in our cohort, the mean mRNA expression was higher in MOC compared with upper GI tumors (Supplementary Fig. S8), including in comparison with pancreatic tumors alone (P = 0.006; Supplementary Fig. S8). Here, MEP1A is linked to pancreatic neoplasm.