MAPK8 and neoplasm: Indeed, blocking JNK signaling by overexpression of a dominant-negative form of Drosophila JNK Basket (BskDN) canceled the tumor-suppressive activity of miR-306 or miR-79 against RasV12/dlg-/- or RasV12/lgl-/- tumors (Figure 3R–W, quantified in Figure 3X, and Figure 3—figure supplement 3A–C, quantified in Figure 3—figure supplement 3D), while BskDN did not affect growth of normal tissues (Figure 3Q compare to Figure 3A, quantified in Figure 3X).