Dampening the activation of the innate immune system by ADAR2 activity is part of mesothelioma similar carcinogenesis mechanisms including mutations in the E3 ubiquitin ligase FBXW7 (F‐box/WD repeat containing protein) tumor suppressor gene [4, 87, 88, 89], which impairs post‐transcriptional stabilization of dsRNA sensors [90]. This evidence concerns the gene ADARB1 and mesothelioma.