CARD14 and psoriasis: In an earlier study, Jordan et al reported 23 CARD14 gene variants, mainly in patients with psoriasis vulgaris.[22] Later, more genome-wide association studies reported more concerning the association of CARD14 gene variants and psoriasis vulgaris as well as other forms of psoriasis.[1,29,31] In our study we found 4 CARD14 gene SNPs that are significantly associated with psoriasis vulgaris.