For instance, the miR-34b family is a well-known cancer suppressor.[23] hsa-miR-129-5p is down-regulated in lung cancer tissues.[24] The down-regulation of PART1 can hinder the occurrence and development of liver cancer by targeting the hsa-miR-3529-3p/FOXC2 axis.[25] The hsa-miR-365b-3p has been identified as a novel miRNA described in various types of tumor including non-small cell lung cancer[26] and hepatocellular carcinoma.[27] miR-491-5p inhibits the proliferation and migration of A549 cells by forkhead box P4.[28]. The gene discussed is FOXC2; the disease is hepatocellular carcinoma.