IFNG and autoimmune disease: The comorbidities present in patients with T marneffei infections include malignancies, organ transplantation, autoimmune diseases, and some emerging conditions such as adult-onset immunodeficiency associated with anti-interferon gamma antibodies, T lymphocyte-depleting immunosuppressive drugs, and novel targeted anticancer agents such as anti-CD20 monoclonal antibodies and kinase inhibitors.