Chondroitin sulfate proteoglycan 4 (CSPG4), also called neural-glial 2 (NG2), is a cell surface proteoglycan, overexpressed in certain human cancers, with low expression in normal tissues and oncogenic roles in tumor growth and metastatic dissemination [12] via the promotion of cell proliferation, cell survival and drug resistance, angiogenesis, cell migration and invasion [13]. The gene discussed is CSPG4; the disease is neoplasm.