For instance, B cell translocation gene 2 (BTG2) is a p53-induced tumor suppressor gene and has been reported to be involved in tumor proliferation, migration, invasion and other processes [28]; the level of gene body 5hmC signals on BTG2 was decreased in all DLBCL samples compared with healthy control samples (Fig. 3C). This evidence concerns the gene BTG2 and diffuse large B-cell lymphoma.