Ultimately, based on our MCIA, we identified CD15, CD104 (Integrin-β4), CD324 (E-cadherin), CD326 (EpCAM), and CD49f as biomarkers for colon cancer and CD24, CD26 (DPP4), CD106 (VCAM1), TIM-1, SSEA-3 (B3GALT5), SSEA-4 (TMCC1), TRA-1-60-R (PODXL) and EGFR for renal cancer. The gene discussed is ITGB4; the disease is colonic neoplasm.