In the distinction between the disease groups, plasma NfL showed a moderate accuracy in differentiating FTD from the other disease groups (AD+PSP+CBS+DLB) (cutoff > 31.3 pg/ml, sensitivity 72.9%, specificity 74.3%, AUC 0.761) with a similar diagnostic performance against each group (Fig. 2). Here, NEFL is linked to frontotemporal dementia.