Finally, while the number of patients with MDS-associated evolution was small, particularly among those with adult-onset AA, the effects of HPA and HLA-B*14:02 were statistically robust, were in agreement with our previous observations (10), and were supported by recent findings for HLA-B*14:02 from an independent cohort of patients from the NIH (15). The gene discussed is HLA-B; the disease is myelodysplastic syndrome.