BAIAP2L2 [46, 47], pituitary tumour-transforming gene 1 (PTTG1) [48, 49] and complement factor H-related 3 (CFHR3) [50] have also been reported to be overexpressed in many types of human cancer and to promote tumour cell angiogenesis, migration and invasion. Here, CFHR3 is linked to cancer.