In this study, we found that the incidence of anemia in patients with bone trauma was 47.09%(494/1049), ranging from 29.74% of hemoglobin (Hb) levels below 10 g/dL to 63.30% of hemoglobin levels below 12 g/dL, and postoperative anemia rates as high as 84.94% (894/1049). The gene discussed is GSTM1; the disease is anemia (phenotype).