TNF and interstitial lung disease: In ROC analyses, serum levels of eotaxin, KL-6 and TNFα distinguished combined subgroups of pSS–ILD (ILA score 2 + 3) from subgroups without definite ILD, with respective AUCs of 0.695 (95% confidence interval: 0.571–0.818, p = 0.006), 0.883 (95% confidence interval: 0.798–0.969, p < 0.0001), and 0.656 (95% confidence interval: 0.527–0.785, p = 0.086) (Table 3).