Although there have been no reports on eotaxin in the context of pSS–ILD, other studies have shown that eotaxin directly affects lung fibroblasts by upregulating procollagen type I gene expression and collagen protein production in lung fibroblasts—suggesting a potential contribution of this CC chemokine to deposition of extracellular matrix (ECM) and the early phase of tissue remodeling in the lung [24]. Here, COL1A2 is linked to interstitial lung disease.