CD40LG and interstitial lung disease: The combined pSS–ILD group (ILA 2 + ILA 3) had higher circulating levels of IgM than the group consisting of pSS–indeterminate and pSS–no ILD (p = 0.029) (Table 2), yielding an AUC of 0.653 (95% confidence interval: 0.521–0.785, p = 0.029) (Table 3).