High EMP3 expression is associated with a worse overall survival rate [Hazard ratio (HR) = 1.71; 95% confidence interval (CI) = 1.32–2.22; p < 0.0001] and progression-free survival in gastric cancer (HR = 1.99; 95% CI = 1.45–2.72; p < 0.0001). The gene discussed is EMP3; the disease is gastric cancer.