Several genes encode proteins with probable roles in sensillum construction and/or maintenance, encompassing OSN cilia morphogenesis (e.g., CG45105, an ortholog of human SDCCAG8, which is implicated in ciliopathies [74]) and cuticle formation (e.g., Vajk3 [75]); some of these may contribute to the distinctive ultrastructural properties of different sensillar classes [12, 40, 41]. The gene discussed is SDCCAG8; the disease is ciliopathy.