The data extracted included the following: (1) basic information of the study, including first author, publication year, country, study design, study interval, study objective, and sample size; (2) baseline characteristics of the research subjects, including the number of patients, age, the primary location and metastatic site of the tumor, microsatellite status, genotype, and PD-L1 status; and (3) outcome measures data. This evidence concerns the gene CD274 and neoplasm.