MTOR and acute respiratory distress syndrome: Similarly, Phase 3 trials of the anesthetic sevoflurane, also studied in the broader context of ARDS, (NCT04355962; NCT04415060), the PPAR alpha agonist fenofibrate (NCT04661930), the calcineurin inhibitor cyclosporine (NCT04979884) and mTOR inhibitor rapamycin (Sirolimus)(NCT04948203) are currently active, with some recently completed.